Pico question examples women - Aug 24, 2023 · PICO (T) Evidence-based practice uses the PICO (T) model for formulating a searchable question. PICO (T) is a mnemonic used to describe the four elements of a good clinical foreground question: P = Population/Problem. How would I describe the problem or a group of patients similar to mine? I = Intervention.

 
PICOT QUESTION PAPER: INFERTILITY Significance to Nursing In nursing, fertility is a process that begins from the second a woman states she is attempting to become pregnant but is having difficulty. Nurses are also educators, so a main component to treating a woman who has fertility issues is to make them aware of their options and issues.. Italian fashion brand that sells dollar650 hair clips

Aug 9, 2023 · PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy. These are some best examples of PICOT questions for falls. 2) The Prognosis. These questions are used in the following scenarios. Used to determine the potential complications from a specific condition or the clinical course over a particular period. The following is an example of an intervention PICOT question:Aug 16, 2023 · 2. Foreground questions are specific knowledge questions . that affect clinical decisions and ; include a broad range of biological, psychological, and sociological issues. Foreground questions are best suited to the PICO model as it captures the essential elements of your information need to help translate that question into a search query. To ... Below are examples of nursing related questions: Intervention/Effect/Therapy PICO Question: An example: In adult patients with total hip replacements (Patient population) how effective is early ambulation (Intervention of interest) compared to bed rest (Comparison intervention) on decreasing post-op DVTs (Outcome)? Note: The question may also ...Aug 3, 2023 · PICO Question Examples It will be a time-consuming and difficult venture to identify the most appropriate resources and find relevant evidence without a well-focused question. PICO helps to form a question and facilitate quick and wider literature search.PICO framework helps to identify the main elements of a question and simplify writing a ... Aug 16, 2023 · 2. Foreground questions are specific knowledge questions . that affect clinical decisions and ; include a broad range of biological, psychological, and sociological issues. Foreground questions are best suited to the PICO model as it captures the essential elements of your information need to help translate that question into a search query. To ... Aug 29, 2023 · Foreground questions look for answers to specific patients, problems, types of interventions, and clinical outcomes, and the PICO framework will work well with these questions. Use PICO to write a clear, researchable clinical question. The four elements of PICO break a research topic into searchable keywords and make locating evidence-based ... If you are planning to create a systematic review, it is usually best to start with a PICO style question, it provides structure and boundaries to the task. Let’s try: To search for the core topics discussed in your review, you are probably going to want to use a combination of approaches. You are probably going to need to use the subject ...“The question needs to identify the patient or population we intend to study, the intervention or treatment we plan to use, the comparison of one intervention to another (if applicable) and the outcome we anticipate,” Kathy A. Jensen, MHA, RN, wrote in EBSCO Health’s whitepaper, “7 Steps To The Perfect Pico Search.” “Once a well ... We would like to show you a description here but the site won’t allow us. Sep 26, 2020 · The word PICOT is a mnemonic derived from the elements of a clinical research question – patient, intervention, comparison, outcome and (sometimes) time. The PICOT process begins with a case scenario, and the question is phrased to elicit an answer. “The question needs to identify the patient or population we intend to study, the ... PICO: P = population; I = intervention; C = comparator; O = outcome(s)[ref]For further information on the findings of the reviews based on the PICOs presented in this annex, refer to the EtD frameworks in Supplementary material 2.[/ref] Pre-abortion Rhisoimmunization PICO 1: No anti-D administration in unsensitized Rh-negative individuals seeking abortion (see Recommendation 8 [NEW]) My advice: set your question based upon what you are interested in answering. For example what if you were interested in knowing "How do side effects, both physical and psychological, effect women who have experienced treatment for cervical cancer.."-radiation therapy, sex drive/life, effects of ADL's etc...PICO is a popular mnemonic in nursing. P stands for Patient/Problem, I for Intervention, C for Comparison, and O for Outcome. PICOT is used by nursing students to generate answers to seemingly vague questions. PICOT question examples such as “How effective is handwashing in reducing infections?” can be broken down in the following manner:PICOT: This evidence-based project answered the following question: In rehabilitation patients, what is the effect of a nurse-driven protocol (NDP) CAUTI bundle on the number of indwelling urinary catheter-related infections, compared to the current practice, over a 12-week time period? EvidencePICOT questions fall into four types, namely: prevention/therapy, diagnosis, etiology, and prognosis. The PICOT format assists in creating a useful clinical question and searching for relevant publications and studies. For instance, if a nurse desires to understand the effect of flu vaccination on the advancementAug 28, 2023 · PICO. PICO is a mnemonic used to help you clarify your clinical question. It acts as a framework, asking you to think specifically about different aspects of what you want to investigate. As you build your PICO, you should make sure that you are clear and specific about what you are looking for. This helps you target the right evidence to use ... You need to assess what reasonable clinical study population your patient could be part of. For example, if your patient is a 73 year old woman, "73 year old women" or "women in their 70s" is too specific because it is highly unlikely that clinical researchers would design a study that would exclusively enroll women in their 70s.Sep 15, 2022 · P: laboring women delivering in a hospital I: positions other than the lithotomy position C: lithotomy position O: decreased incidence of assisted deliveries In laboring women delivering in the hospital, do positions other than lithotomy position lead to a decreased incidence of assisted deliveries? PICO Clinical Questions in Obstetrics & Gynaecology Prof Unit Kalubowila. 866 likes · 10 talking about this. Novel concept of Dr Dhammike Silva, Consultant OBGYN, to inspire trainees to approach...PICO Question: Methods Evidence •Kennard, et al (2006) found a significantly higher remission rate in the SSRI + CBT group (37%) relative to the other treatment groups (SSRI 23%; CBT 16%; placebo, 17%). •Suggests combination therapy (SSRI + CBT) is superior to monotherapy, regardless of whether it is SSRI alone or CBT alone.My advice: set your question based upon what you are interested in answering. For example what if you were interested in knowing "How do side effects, both physical and psychological, effect women who have experienced treatment for cervical cancer.."-radiation therapy, sex drive/life, effects of ADL's etc...Jul 17, 2021 · PICOT Question. The emotional wellbeing of mothers is linked to the positive upbringing of children in the first several months of their lives. However, the physical, hormonal, and psychological changes that occur after labor can significantly undermine women’s well-being, with adverse symptoms preventing them from having a positive outlook on lives. PICOT Questions Evidence-Based PICOT Questions Examples. PICOT Questions: Population: Bariatric adolescents considering or undergoing gastric bypass surgery.. Intervention: The nurse’s role as a primary member of the multidisciplinary team regarding perioperative care of the bariatric adolescent patient.Aug 18, 2023 · PICOT is different from a standard research question because it is a clinical question. It is composed of various elements that create a framework for research that typical research questions do not usually have. The goal or purpose of PICOT is to ultimately intervene in someone's healthcare. Focus on prevention. PICOT 7 PMTCT What is the most effective antiviral therapy during the third trimester of pregnancy, to reduce transmission of HBsAg? P: Pregnant women in the third trimester of pregnancy (defined as 27–40 weeks gestation) with chronic hepatitis B virus infection (positive for HBsAg persistently for more than 6 months) (stratified by HBeAg ...PICO Question: Methods Evidence •Kennard, et al (2006) found a significantly higher remission rate in the SSRI + CBT group (37%) relative to the other treatment groups (SSRI 23%; CBT 16%; placebo, 17%). •Suggests combination therapy (SSRI + CBT) is superior to monotherapy, regardless of whether it is SSRI alone or CBT alone. PICO Question: Methods Evidence •Kennard, et al (2006) found a significantly higher remission rate in the SSRI + CBT group (37%) relative to the other treatment groups (SSRI 23%; CBT 16%; placebo, 17%). •Suggests combination therapy (SSRI + CBT) is superior to monotherapy, regardless of whether it is SSRI alone or CBT alone.Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3Jan 20, 2010 · Clinical questions could arise in situations such as the following: You become uncertain, during a patient encounter, about the desirability of a particular diagnostic or therapeutic choice. You encounter a product advertisement in a journal in which you are encouraged to purchase and use a particular technology for your patients. Question Type & Study Design. Some study designs are better suited to answer certain types of questions. Identifying the clinical domain your question falls under can help determine what study designs to look for in order to find the best, most suitable evidence. Systematic Reviews and Meta-Analyses are always preferred.Have two essential components: Example: What causes migraines? or How often should women over the age of 40 have a mammogram? A question root (who, what, when, etc.) with a verb; A disorder, test, treatment, or other aspect of healthcare; The background question is usually asked because of the need for basic information.Below are examples of nursing related questions: Intervention/Effect/Therapy PICO Question: An example: In adult patients with total hip replacements (Patient population) how effective is early ambulation (Intervention of interest) compared to bed rest (Comparison intervention) on decreasing post-op DVTs (Outcome)? Note: The question may also ...Aug 28, 2023 · PICO. PICO is a mnemonic used to help you clarify your clinical question. It acts as a framework, asking you to think specifically about different aspects of what you want to investigate. As you build your PICO, you should make sure that you are clear and specific about what you are looking for. This helps you target the right evidence to use ... These are some best examples of PICOT questions for falls. 2) The Prognosis. These questions are used in the following scenarios. Used to determine the potential complications from a specific condition or the clinical course over a particular period. The following is an example of an intervention PICOT question:Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to: PICOT is a mnemonic resulting from the elements of clinical research. The PICOT process starts with a particular case, and the question is couched to develop an answer. A PICOT question helps you get the answer to your clinical question. It serves as a framework, prompting you to consider various aspects of the topic under investigation. Apr 20, 2021 · Introduction. Stroke is a medical condition that is caused by the interruption or reduction of blood supply to the brain. This deprives the affected part of brain nutrients and oxygen supply. The biochemical processes are hence stopped, interrupted, or impaired; the brain cells can even die. Further, the condition can also be caused by bursting ... Table 2.1, PICO questions for the recommendations in women (the general population of women ...Application to PICO. The articles chosen for the analysis related to the PICO question: “In the second stage of labor, what is the effect of laboring down after complete cervical dilation on mother and baby compared with pushing before cervical dilatation is complete?” The population that wasI = Interventions. C = Comparisons. O = Outcomes. Using the earlier example question, we can break it down into a PICO question like this: P = Patient or Problem (young children) I = Interventions (distractions during immunization) C = Comparisons (no distractions/standard care) O = Outcomes (lower pain scores) You may also hear some people use ...If you are planning to create a systematic review, it is usually best to start with a PICO style question, it provides structure and boundaries to the task. Let’s try: To search for the core topics discussed in your review, you are probably going to want to use a combination of approaches. You are probably going to need to use the subject ...If you are planning to create a systematic review, it is usually best to start with a PICO style question, it provides structure and boundaries to the task. Let’s try: To search for the core topics discussed in your review, you are probably going to want to use a combination of approaches. You are probably going to need to use the subject ...Use the PICOT format to structure your literature search based on a clearly-stated, searchable clinical question. P = Patient Population. I = Intervention or area of Interest. C = Comparison or Control group. O = Outcome.Jul 7, 2023 · These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances. The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates.Evidence-Based Nursing. Evidence-based nursing is the use of evidence in combination with the practitioner's expertise and nursing theory in order to make decisions about nursing patient care. It consists of 5 stages: Asking a question after assessing the patient. Acquire the evidence by finding literature to answer the question.Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3PICO Clinical Questions in Obstetrics & Gynaecology Prof Unit Kalubowila. 866 likes · 10 talking about this. Novel concept of Dr Dhammike Silva, Consultant OBGYN, to inspire trainees to approach... The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO nursing questions. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention.Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ... PICO (T) Evidence-based practice uses the PICO (T) model for formulating a searchable question. PICO (T) is a mnemonic used to describe the four elements of a good clinical foreground question: P = Population/Problem. How would I describe the problem or a group of patients similar to mine? I = Intervention.Jul 17, 2021 · PICOT Question. The emotional wellbeing of mothers is linked to the positive upbringing of children in the first several months of their lives. However, the physical, hormonal, and psychological changes that occur after labor can significantly undermine women’s well-being, with adverse symptoms preventing them from having a positive outlook on lives. PICOT is an acronym that is used to represent the clinical question: (P) Patient population, or group of patients of interest. (I) Intervention, treatment, or issue of interest. (C) Comparison or alternative intervention, or issue of interest. (O) Outcome (s) of interest. (T) Time for intervention to achieve or demonstrate the outcome.Developing a Targeted Research Question. Examine your topic to identify the major concepts you need to conduct the best searches. Some useful ways to do this include: Background planning: think of the 5 W's and H for your topic: Who - are the stakeholders, population of interest, involved parties. What - are the issues, problems, needs.Below are examples of nursing related questions: Intervention/Effect/Therapy PICO Question: An example: In adult patients with total hip replacements (Patient population) how effective is early ambulation (Intervention of interest) compared to bed rest (Comparison intervention) on decreasing post-op DVTs (Outcome)? Note: The question may also ...We would like to show you a description here but the site won’t allow us.These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances.Below are examples of nursing related questions: Intervention/Effect/Therapy PICO Question: An example: In adult patients with total hip replacements (Patient population) how effective is early ambulation (Intervention of interest) compared to bed rest (Comparison intervention) on decreasing post-op DVTs (Outcome)? Note: The question may also ...Jun 14, 2023 · A good PICO will be specific and define terms and outcomes if necessary. A good PICO will investigate something new in terms of diagnosis, etiology, therapy, harm, etc. A bad PICO is usually a background question disguised as a research question. For example, "what are the effects of Prilosec on patients taking immune suppressants" might seem ... • Discuss the background questions as a group, and look up the answers as needed. • Find the answer to the foreground question, or have everyone write their own PICO question. • Take 5 minutes to look up the PICO answers. • Share the PICO answers and resources used. PICO and 2×2 table for question about test accuracy. Population of interest=women aged 40–74 years without a history of breast cancer. Investigated test result=positive result on mammography. Comparator test result=negative result on mammography. Outcome=breast cancer according to biopsy (or not) View inline. What PICO means. P: Population/disease ( i.e. age, gender, ethnicity, with a certain disorder) I: Intervention or Variable of Interest (exposure to a disease, risk behavior, prognostic factor) C: Comparison: (could be a placebo or "business as usual" as in no disease, absence of risk factor, Prognostic factor B ) O: Outcome: (risk of disease ...Develop and revise questions that focus your inquiry. Create a concept map that demonstrates the relationships between concepts. Once you have selected your topic area and reviewed literature related to it, you may need to narrow it down to something that can be realistically researched and answered. In the last section, we learned about asking ...Below are examples of nursing related questions: Intervention/Effect/Therapy PICO Question: An example: In adult patients with total hip replacements (Patient population) how effective is early ambulation (Intervention of interest) compared to bed rest (Comparison intervention) on decreasing post-op DVTs (Outcome)? Note: The question may also ...Oct 15, 2019 · The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention. Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to: Level of Evidence What is a PICO Question? PICO is an acronym used for exploring clinical questions. It serves as a framework for evidence-based practice. P (Problem and Population) What health problem is your selected intervention intended to solve? Identify what population of people will benefit the most from your chosen intervention.Formulate a PICO Question . Answerable PICO Question: In middle-aged adult females with hypertension, are beta blockers more effective than ACE inhibiters in controlling blood pressure? Image: "Dagstuhl 2008-02-01 - 37" by Nic's events is licensed under CC BY-SA 2.0Finally, you will click on a button and the PICOT Research Question Generator will present the following: Your PICOT question. Your null and alternative hypotheses. Your independent variable. Your dependent variable. The statistical test used to answer your PICOT question. It should take you less than five minutes to complete the web form below.The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO nursing questions. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention.25 Clinical Questions and PICO. The use of PICO is very relevant in the construction of your clinical questions. Evidence-based nursing assignments demand you to structure your research questions in accordance with the PICO framework. The PICO framework is divided into four major elements. These elements will help you frame the background ...The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO nursing questions. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention.Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ...Aug 15, 2023 · [Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ... Mar 23, 2023 · Developing a Targeted Research Question. Examine your topic to identify the major concepts you need to conduct the best searches. Some useful ways to do this include: Background planning: think of the 5 W's and H for your topic: Who - are the stakeholders, population of interest, involved parties. What - are the issues, problems, needs. A strength of a qualitative PICO question is that it can investigate what patient satisfaction looks like, for example, instead of only reporting that 25% of patients who took a survey reported that they are satisfied. When working with qualitative questions, an alternative to using PICO in searching for sources is the SPIDER search tool.Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3PICOT 7 PMTCT What is the most effective antiviral therapy during the third trimester of pregnancy, to reduce transmission of HBsAg? P: Pregnant women in the third trimester of pregnancy (defined as 27–40 weeks gestation) with chronic hepatitis B virus infection (positive for HBsAg persistently for more than 6 months) (stratified by HBeAg ...Jul 7, 2023 · These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances. Sep 21, 2019 · The list of PICOT question examples will be incomplete if we didn’t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ...

Aug 3, 2023 · PICO Question Examples It will be a time-consuming and difficult venture to identify the most appropriate resources and find relevant evidence without a well-focused question. PICO helps to form a question and facilitate quick and wider literature search.PICO framework helps to identify the main elements of a question and simplify writing a ... . Failed to create a personal access token for this user in azure devops

pico question examples women

PICO Clinical Questions in Obstetrics & Gynaecology Prof Unit Kalubowila. 866 likes · 10 talking about this. Novel concept of Dr Dhammike Silva, Consultant OBGYN, to inspire trainees to approach...PICO Clinical Questions in Obstetrics & Gynaecology Prof Unit Kalubowila. 866 likes · 10 talking about this. Novel concept of Dr Dhammike Silva, Consultant OBGYN, to inspire trainees to approach...PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy.Aug 15, 2023 · [Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ... When constructing your PICO question, a few important points to bear in mind: Your patient is a member of a population as well as a person with (or at risk for) a health problem . Factors to consider include age, sex, comorbid conditions, past medical history, socioeconomic status or other demographic variables, as these factors may impact your ...About PICO; PICO's Limitations; Case Study. Case: Patient Education; P: Consider when choosing your patient/problem; I: Consider for your intervention; C: Consider for your comparison; O: Consider for your outcome; PICO: Putting it together; PICO Examples; Other Question Frameworks; ResourcesMay 26, 2015 · "Among women in labor, does the use of labor support/doulas versus no labor support affect labor complications?" (PICOt Question example by M. Montgomery) (PICOt Question example by M. Montgomery) Types of Questions: Therapy, Diagnosis, Prognosis, Harm/Etiology, Prevention, Cost-Effectiveness, Quality of Life. PICOT QUESTION PAPER: INFERTILITY Significance to Nursing In nursing, fertility is a process that begins from the second a woman states she is attempting to become pregnant but is having difficulty. Nurses are also educators, so a main component to treating a woman who has fertility issues is to make them aware of their options and issues.PICO Clinical Questions in Obstetrics & Gynaecology Prof Unit Kalubowila. 866 likes · 10 talking about this. Novel concept of Dr Dhammike Silva, Consultant OBGYN, to inspire trainees to approach...PICOT is an acronym that is used to represent the clinical question: (P) Patient population, or group of patients of interest. (I) Intervention, treatment, or issue of interest. (C) Comparison or alternative intervention, or issue of interest. (O) Outcome (s) of interest. (T) Time for intervention to achieve or demonstrate the outcome.“The question needs to identify the patient or population we intend to study, the intervention or treatment we plan to use, the comparison of one intervention to another (if applicable) and the outcome we anticipate,” Kathy A. Jensen, MHA, RN, wrote in EBSCO Health’s whitepaper, “7 Steps To The Perfect Pico Search.” “Once a well ... According to Melnyk & Fineout-Overholt (2019), a randomized control trial is considered level II evidence for my PICOT question. The article by Pope et al. (2016), is a case control, cross sectional design, which would be classified as level IV evidence (Melnyk, Fineout-Overholt, 2019).CHAPTER SUB-CHAPTER QUESTION; 3. Problems of the neonate and young infant: 3.1 Routine care of the newborn at delivery: Among healthy newborn infants in low- and middle-income countries (P), does early skin-to-skin contact of the baby with the mother in the first hour of life (I) compared with drying and wrapping (C) have an impact on neonatal mortality, hypothermia or initiation/exclusivity ...Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to:PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy..

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